Malazan Empire: COVID-19 (aka Coronavirus, aka 2019-nCoV) - Malazan Empire

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COVID-19 (aka Coronavirus, aka 2019-nCoV)

#3421 User is offline   Azath Vitr (D'ivers 

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Posted 20 November 2022 - 10:45 PM

'Eric Topol
@EricTopol
I'm outraged by this pathetic and inexcusable inability for this country to go after nasal and better, durable, variant-proof vaccines

"U.S. FALLS BEHIND
ON COVID VACCINES

'WARP SPEED' SET BACK

Prospects Dim for Nasal
Sprays and Universal
Shots for Variants"

An explainer for why the US is not pursuing nasal vaccines. TLDR: there is no good explanation

The End of Covid Vaccines at 'Warp Speed' - The New York Times (nytimes.com)
'

Eric Topol on Twitter: "I'm outraged by this pathetic and inexcusable inability for this country to go after nasal and better, durable, variant-proof vaccines https://t.co/CuRQ51q8pi" / Twitter

'Efforts to test and produce next-generation Covid vaccines are bogged down by bureaucratic problems and funding shortfalls. Foreign rivals have raced ahead in approving long-awaited nasal-spray vaccines, including one invented in St. Louis, creating a scenario in which Americans would have to travel abroad for the latest in American vaccine technology.

The Biden administration has launched a last-ditch effort to restore the country's edge. [...] Biden asked the lame-duck session of Congress this week for $5 billion for next-generation vaccines and therapeutics, as part of a broader $9.25 billion pandemic spending request. But Republicans, having blocked requests for next-generation vaccine funding since the spring amid complaints about how the White House spent earlier pandemic aid allocations, have shown no signs of dropping their resistance.

[...] No next-generation vaccines are as close at hand, or as likely to reduce the spread of the virus, as those that can be inhaled or sprayed into the nose. [...]

China, India, Russia and Iran have all approved vaccines delivered through the nose or the mouth, even though they have not released much data about how the products work.

In the United States, nasal sprays have been held back by the same funding constraints and logistical hassles that, before the pandemic, often made developing vaccines a decade-long ordeal. [...]

"It went back to the prepandemic speed of vaccine development," [...] His team's nasal vaccine has undergone its most advanced testing in Mexico; collaborating with a pharmaceutical company there offered the fastest path to clinical trial funding. In the United States, he said, "The funding situation is pretty dire."

[...]

Last month, a nasal version of the Oxford-AstraZeneca vaccine failed in a trial[...]

"It's a fundamentally more difficult venture than a shot in the arm, which we've been doing for over 100 years," [...]

The chances of any one candidate failing have discouraged America's largest vaccine makers from investing. [...]

[...] What is missing, scientists said, is money for pushing those vaccines out of university laboratories and into real-world studies now that they are urgently needed.

"We're at the last mile," [...] The costs of speeding up testing, he said, paled in comparison to the risks of waiting.'

This post has been edited by Azath Vitr (D'ivers: 20 November 2022 - 10:47 PM

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