Tom;137269 said:
The problem with picking up a book from the middle of the Dune series is that the first book remains the essential basis for understanding what the heck is going on in the meta-story. Without it, you lose the impact of the complete Atreides/Fremen Titanomachia and miss what the God Emperor is trying to accomplish/avoid with his Golden Path.
Picking up the plot threads piecewise may be a viable strategy with other authors, but Herbert (Frank) needs to be read in proper sequence for full appreciation.
Side note: I actually liked Chapterhouse. It's too bad Herbert left us with a similar situation to Mervyn Peake's Titus series.